Hypersensitivity, coma, porphyria, cardiac disease, hypokalaemia, intra-arterial or SC inj, neonates and young children, pregnancy, lactation An understanding of the pathophysiology of nausea and the mechanisms of antiemetics can help family physicians improve the cost-effectiveness and efficacy of therapy. The interest in promethazine. Newborn/premature infants. DESCRIPTION: Blocks cholinergic receptors in the vomiting center, which may mediate nausea and vomiting; competes with histamine phenergan hypersensitivity for the H1 receptor site. SC or intra-arterial administration. SC or intra-arterial administration. Sharing the following safe practices in using promethazine with physicians, pharmacists, and nurses may facilitate discussion Contra-Indications: Hypersensitivity to phenothiazines, in patients with glaucoma or those in a coma due to CNS depressants. Phenergan Sugar Free (orange flavour) Elixir should not be given to patients with allergies to sodium metabisulfite, sodium sulfite or sodium benzoate It is used to treat allergies, trouble sleeping, and nausea. Phenergan Sugar Free (orange flavour) Elixir should not be given to patients with allergies to sodium metabisulfite, sodium sulfite or sodium benzoate • History of an idiosyncratic reaction to promethazine or to other phenothiazines. (4) • Hypersensitivity to codeine or other opiates, promethazine, or any of the inactive ingredients in Promethazine HCl and Codeine Phosphate Oral Solution. (4)-----WARNINGS AND PRECAUTIONS ----- -----See Boxed WARNINGS. · hypersensitivity to one of its components (promethazine, paraben, lanolin or wool fat), · seeping dermatosis · infected dermatosis · eczema 4.4. Multiple Phenergan Uses. Nausea and vomiting are. When histamine binds to its receptors on cells, it. Promethazine hydrochloride (Phenergan) is an antihistamine that relieves nasal stuffiness and inflammation and red, inflamed eyes caused by hay fever and other allergies, treats itching, swelling, and redness from hives and other rashes, allergic reactions to blood transfusions, a sedative and sleep aid for both children and adults, prevents and controls nausea and vomiting before and after. Precautions: Promethazine can potentiate CNS depressants such as barbiturates, narcotics, analgesics, and general anesthetics; therefore, dosages of these. It is used to treat allergies, trouble sleeping, and nausea. Phenergan Elixir should not be given to patients with allergies to sodium metabisulfite, sodium sulfite or sodium benzoate Phenergan Elixir 5mg/5ml Oral Solution. The labeling on all brand name and generic products has been changed to reflect these strengthened warnings. It is used to treat allergies, trouble sleeping, and nausea. Genetic Implication Promethazine hydrochloride injection, USP is a sterile, pyrogen-free solution for deep intramuscular or intravenous administration. Promethazine is not recommended for infants below 2 years of age. 2 years old (risk of potentially fatal respiratory depression). Some of the dosage forms listed on this page may not apply to the brand name Promethazine with Dextromethorphan For the Consumer. It is contraindicated in children under 2 years of age due to the risk of potentially fatal respiratory depression Known hypersensitivity or idiosyncrasy to promethazine or other phenothiazines. 2 years old (risk of potentially fatal respiratory depression).
Promethazine is contraindicated for use in patients with a history of hypersensitivity to the drug substance, substances of similar chemical structure or hypersensitivity to the other ingredients. Interestingly, promethazine is one of the phenothiazines, a group of medicines known for their torsadogenic properties Parenteral ranitidine is used as a premedication of hypersensitivity reaction (HSR) to paclitaxel. Present in all research and its aetiology Promethazine is a first-generation antihistamine. US Pharm. The following information is NOT intended to endorse any particular medication. Hx of prior idiosyncratic / hypersensitivity reactions to Promethazine Allergy to sulfites (contains sulfite preservative) Children under 2 y.o. Promethazine is a first-generation antihistamine. The pH range is 4.0 to 5.5, buffered with acetic acid-sodium acetate, and it is sealed under nitrogen Promethazine hydrochloride (promethazine hydrochloride. prochlorperazine, chlorpromazine) or other agents likely to increase extrapyramidal reactions concomitant use of tiotropium or ipratropium. P roblem: Promethazine (Phenergan, Wyeth) is a commonly used injectable product that possesses antihistamine, sedative, anti-motion sickness, and anti-emetic effects.The drug is also a known vesicant that is highly caustic to the intima of blood vessels and surrounding tissue. have already proposed pharmacokinetic bioequivalence with oral drug formulation without clinical validation in terms of EBM. Formulated with phenol, promethazine has a pH between 4 and 5.5 Promethazine contraindications include patients with hypersensitivity to the drug, any components of the drug, or other phenothiazines. Drug hypersensitivity reactions and allergic conditions have also been treated with promethazine especially in emergencies Phenergan: [ fen´er-gan ] trademark for preparations of promethazine , an antihistamine , antiemetic , and sedative hypersensitivity or prior adverse reaction to promethazine concomitant use of phenothiazines (i.e. It may help with some symptoms associated with the common cold. Contraindications. Dogs with allergies or hypersensitivity disorders respond to Phenergan. Hypersensitivity to meperidine or promethazine. Coma. Phenergan Injection should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression Warning. Under no circumstances should Phenergan Injection be given by intra-arterial injection due to the. Chiu on phenergan antihistamine: Phenergan (promethazine) is a pretty good medication for symptomatic treatment of nausea Promethazine is a drug that has been on the market for more than 50 years but, to date, the data about its arrhythmogenic potential are rather sparse. Under which the person may experience angioneurotic edema, tightening of the chest, difficulty breathing, itchy feeling, swelling, redness, rashes and the like Promethazine should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Interestingly, promethazine is one of the phenothiazines, a group of medicines known for their torsadogenic properties Promethazine has not been reliably detected in breast milk. Its anti-emetic properties are also useful and it was found to be signiﬁcantly more effective than ondansetron for treating postoperative nausea and vomiting (PONV) after failed prophylaxis with this 5-HT 3 blocker . Note: This document contains side effect information about dextromethorphan / promethazine. Promethazine is contraindicated for use in patients with a history of hypersensitivity to the drug substance, substances of similar chemical structure or hypersensitivity to the other ingredients. Phenergan Sugar Free (orange flavour) Elixir should not be given to patients with allergies to sodium metabisulfite, sodium sulfite or sodium benzoate [8–10] and prevention of hypersensitivity reactions to various drugs . Hypersensitivity This is a rare form and part of the Phenergan side effects which is hypersensitivity. Phenergan Injection is contraindicated in comatose states and in patients who have demonstrated an idiosyncratic reaction or hypersensitivity to promethazine or other phenothiazines. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of phenergan hypersensitivity healthcare practitioners Phenergan contains Sodium Sulphite and may rarely cause severe hypersensitivity reactions and bronchospasm.